Which medication is typically administered to help with severe nausea during pregnancy?

Metoclopramide is a medication that is often administered to help manage severe nausea during pregnancy. It works by enhancing gastric motility and increasing the peristaltic movement in the upper gastrointestinal tract, which can alleviate the symptoms of nausea and vomiting. This is particularly important during pregnancy when women may experience conditions such as hyperemesis gravidarum, which involves severe and persistent nausea and vomiting.

While antihistamines are also used to treat nausea in some cases, metoclopramide is specifically recognized for its effectiveness in more severe situations and is often a preferred choice in clinical settings. Unlike ibuprofen and acetaminophen, which are primarily used for pain relief and fever reduction (and not for nausea), metoclopramide directly addresses the underlying mechanisms of nausea, making it the most suitable option among the listed choices for severe nausea during pregnancy.