What should the nurse prepare for a client with a history of hemolytic disease of the newborn?

In a client with a history of hemolytic disease of the newborn (HDN), preparing for frequent maternal blood evaluations is crucial because it allows healthcare providers to monitor the mother's antibody levels and overall immunological status. In cases of HDN, particularly those related to Rh incompatibility or other alloimmunization, it is essential to assess the maternal serum for antibodies that could influence the fetus's health.

Maternal blood evaluations help in identifying rising titers of antibodies, which indicate an increased risk of fetal hemolysis. This monitoring is vital because elevated antibody levels can lead to serious fetal complications, such as anemia, jaundice, or even heart failure in the fetus.

While placental, amniotic fluid, and fetal blood evaluations are important in some contexts, the primary focus in managing a history of HDN is the maternal evaluation. This is because understanding the mother’s immunological response provides critical insights into potential fetal complications and guides appropriate interventions, such as administering Rh immunoglobulin or preparing for possible intrauterine transfusions.