What is a significant concern regarding advanced maternal age during pregnancy?

Advanced maternal age, typically defined as 35 years and older at the time of delivery, is associated with an increased likelihood of chromosomal abnormalities in the fetus. This concern arises primarily due to the dynamics of oocyte aging. As women age, the quality of their eggs declines, increasing the risk of errors during cell division, leading to conditions like Down syndrome (Trisomy 21) and other chromosomal anomalies.

This higher risk of chromosomal abnormalities is significant because it can impact not just the health of the baby but also the decisions surrounding prenatal screening and potential interventions. Hence, older maternal age is closely monitored in prenatal care for the potential consequences on fetal health. This understanding helps guide healthcare professionals in providing adequate counseling and care to expectant mothers of advanced age.